CLINICAL, IMMUNOLOGICAL, AND MOLECULAR FEATURES OF TYPICAL AND ATYPICAL SEVERE COMBINED IMMUNODEFICIENCY: REPORT OF THE ITALIAN PRIMARY IMMUNODEFICIENCY NETWORK

Severe combined immunodeficiencies (SCIDs) are a group of inborn errors of the immune system, usually associated with severe or life-threatening infections.Due to the variability of clinical phenotypes, the diagnostic complexity and the heterogeneity of the genetic basis, they are often difficult to recognize, leading to a significant diagnostic de

Supported lipid bilayers (SLBs) are low-complexity biomimetic membranes, Dining serving as popular experimental platforms to study membrane organization and lipid transfer, membrane uptake of nanoparticles and biomolecules, and many other processes.Quartz crystal microbalance with dissipation monitoring has been utilized to probe the influence of s

Abstract There is a male preponderance in gastric cancer (GC), which suggests a role of androgen instruments and androgen receptor (AR).However, the mechanism of AR signaling in GC especially in female patients remains obscure.We sought to identify the AR signaling pathway that might be related to prognosis and examine the potential clinical utilit